I thought that I would combine opinion & science in this article to get to the bottom of a commonly stated notion. Ideally, we want a chaser that's not too loaded with sugar, & assist the absorption of constituents in the powdered leaf of Mitragyna speciosa. A lot of people claim grapefruit juice is capable of assisting the herb in being broken down faster and better. Is this true, or is it just hear say? In the next paragraph we will look at some scientific inquiry into this idea, and see if it has any academic credibility.
There is a little science behind this notion and according to some research grapefruit juice has been found to, "be an inhibitor of the intestinal cytochrome P – 450 3A4 system, which is responsible for the first pass metabolism of many drugs."  So these rumors surrounding using grapefruit juice as a chaser may be more than just hear say. The ultimate test is to try it yourself. Results are reported to vary amongst users, and any kind of potentiator over time may be disabled or inhibited by biological functions which seek to counteract to our efforts to increase the effectiveness of such substances.
In other words, if you're body is attempting to turn down the volume on the effects induced by substances of any kind, this is tolerance, and should not be ignored. You're body is doing this for a reason. It doesn't mean that Kratom is bad or that people shouldn't use it, it just means you're body is attempting to lower your intake because your conscious mind is not. It seems to me to be an unconscious measure carried out by the mind body connection. I think that a tolerance break and a chronic lowering of dosages is the best way to get better effects out of anything.
The ideal chaser is something that washes the powdered leaf down smoothly and mask the bitter taste. Water and beer are the two worst chasers because the ground up leaves will just expand in your mouth, plus they seem to exaggerate the bitterness and fowl taste as well. Some people like to pour a dose in some pudding, ice cream, or something similar so that it can be eatn without the Kratom even coming in contact with your tongue. This sounds reasonable enough and has worked for me. You may not always want to eat something every time you go to take a spoon though.
Tea works a little better than water but not much. Since it contains L-theanine, and many of the same phytochemicals as Mitragyna speciosa, it may as a result assist the psychoactive potential of it. L-theanine also increases serotonin in the brain, making it idea to take with our majestic herb. Be weary of doing this too often though, because both substances work with the adrenal system. Over stimulation of your adrenals can lead to adrenal fatigue, leaving you with even less energy than before. This can be confirmed with a quick search. Use "scholarly" after your keywords in google to find academic sources via google's scholarly search feature.
If you are using Kratom for energy, use caution about over-doing it obviously, or using sugary drink with it because excessive consumption of sugar can also cause fatigue and energy loss. Other than grapefruit juice and tea, what makes the best toss and wash drink is merely opinion. Some prefer to use a kratom tincture so a sip of water is all you need to get the taste over with, and it also avoids the use of eating powdered leaf. You can have a slice of lime handy to get rid of the taste also, and this is very simple and gets rid of having to drink sugary liquids with your leaf.
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