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Medicinal/Psychoactive properties and applications: nutmeg its oils have a medical history of use for the nervous and digestive systems; antimicrobial; inhibition of Jurkat cell activity in human leukemia; anticholinergic; Oneirogen(Devereux, Devereux 1998 56); more coming soon.
Culinary: Nutmeg is used in Indonesia for cooking various dishes.
Pharmacological constituents: macelignan, myristicin(maoi), elemicin; oils: volatile fraction typically contains 60-80% d-camphene, d-pinene, limonene, d-borneol, l-terpineol, geraniol, safrol(also found in Sassafras root), myristicin, and Trimyristin.
There's way more to Nutmeg than people think. It's not just a culinary spice that has an incredible flavor. It's chalked full of pharmacological constituents. Some of these are said to be psychoactive and mildly psychedelic. Many of them do have a toxicity in a certain dosage. Keep that in mind because i'm not encouraging the use of this ethnobotanical as a drug and I would like to encourage harm reduction.
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I love this stuff, and especially appreciate it's oneirogenic properties. When metabolized by the body, a psychedelic is created that can greatly assist your minds own neurotransmitters in the induction of incredible dreams. (Devereux, Devereux 1998 56) This active chemical is very closely related to MDMA. If you can isolate the essential oils, they make a great addition to any oneirogen infusion. Oneirogens are plants, drugs, or substances that stimulate or enhance dreams.
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Nutmeg contains Safrole, the psychoactive ingredient found in Sassfras Root. This is what gave the original root beer its psychoactive punch. Cinnamon also contains it. So when you think of Nutmeg, think of Cinnamon and Sassafras, because they all share the same microscopic phytochemicals. They are all examples of how nature creates the same alkaloids in different life forms, time and time again.
It's very important to know that a large enough dosage of the oils can yield toxic results. It doesn't take much. A controlled dosage has proven to be quite the fascinating psychoactive ally from my experience. The myristicin compound is an maoi, which means that when used carefully, it can increase the psychoactive potential of other substances. One must use great caution and conduct thorough research when utilizing this ally. Mixing MAOIS
with the wrong thing can be dangerous.
Whole Nutmeg is wrapped in Mace, which is the same stuff used in the hand held spray used for self defense. It can be easily removed by soaking the whole nuts in warm water. From there, the mace can be easily removed. One can make their own can of mace using it, by simply soaking it in high grade alcohol like everclear. It literally has a million in one uses, and very few people are aware of this.
Research shows that macelignan isolated from M. fragrans (Myristicaceae) may provide antimicrobial activity against Streptococcus mutans, Further research shows that a methanolic extract from the plant inhibited Jurkat cell activity in human leukemia. Streptococcus mutans is basically a cavity.(5) Because of this, I like to use in in
homemade oral hygiene products. I combine it with Myrrh, Echinacea, and Pau Darco, in some high grade everclear. I rinse my mouth out with it twice a day(diluted in alcohol or mixed with listerine).
Warning: Too much nutmeg may exhibit toxic effects. This is very hard to accomplish and one would have to be incredibly foolish for this to even happen. Another way to experience toxicity from consumption of this ethnobotanical would be by a chemist who has isolated and consumed free-based alkaloids from Nutmeg or its oil in too large of a dosage.
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 Devi, P. B.; Ramasubramaniaraja, R. (2009). "Dental Caries and Medicinal Plants – An Overview". Journal of Pharmacy Research 2 (11): 1669–1675. ISSN 0974-6943.
 Chirathaworn, C.; Kongcharoensuntorn, W.; Dechdoungchan, T.; Lowanitchapat, A.; Sa-Nguanmoo, P.; Poovorawan, Y. (2007). "Myristica fragrans Houtt. Methanolic extract induces apoptosis in a human leukemia cell line through SIRT1 mRNA downregulation". Journal of the Medical Association of Thailand = Chotmaihet thangphaet 90 (11): 2422–2428. PMID 18181330.
 Devereux, P., & Devereux, C. (1998). The lucid dreaming book: How to awake within, control and use your dreams. Boston, MA: Journey Editions.